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Corel Medical Series: Cancer
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00079_Field_SRC.c28.A.9.txt
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1997-01-28
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Blood and Other Tests
• A complete blood count (CBC) reveals anemia in two-thirds of
patients.
• An increased total serum protein may be one of the first clues to
the presence of an M-protein. An elevated serum calcium occurs in
about 30 percent of patients. The level of serum creatinine (a
measure of kidney function) is abnormal in more than one-fourth of
patients at diagnosis. The serum beta-2 microglobulin level is
helpful in prognosis .
• Serum protein electrophoresis shows an M-protein "spike" in 80
percent of patients. Immunoelectrophoresis or immunofixation is
necessary to determine the type of M-protein. The amount of
M-protein is measured by serum protein electrophoresis or by the
measurement of IgG or IgA, the two major types of M-protein
found in multiple myeloma .
• Ninety-nine percent of patients with multiple myeloma will have
an M-protein in the blood or in the urine. If the level of M-protein
in the blood is high or if the patient has blurred vision or bleeding,